ICS-2100 Integrated Reagent-Free IC System

ICS-2100 Integrated Reagent-Free IC System


The ICS-2100 system is the first Reagent-Free™ ion chromatography system with electrolytic sample preparation (RFIC-ESP™ system) and eluent generation (RFIC-EG™ system) capabilities designed to perform all types of electrolytically generated isocratic and gradient IC separations using conductivity detection. Microbore 2 mm columns and standard bore 4 mm columns are fully supported.

The ICS-2100 RFIC-ESP system now provides automation for many sample preparation techniques with multiple valving configurations and support for electrolytic sample preparation devices.

The ICS-2100 system provides high performance with unequalled ease-of-use when coupled with an AutoSuppression® device, such as the SRS® 300 suppressor. Chromeleon®software provides full control and digital data collection from a PC using simple USB connectivity.

Key Features:

  • Automated eluent generation
  • LCD front panel control
  • Dual-piston pump
  • Column heater
  • Electrolytic suppression
  • Digital conductivity detection
  • Vacuum degas (option)
  • Optional 6- or 10-port valve
  • Optional RFIC-ESP water purifier
  • USB connectivity, plug-n-play
  • Electronic logbook and trending through virtual channels


  • RFIC-ESP system accessories enable control of electrolytic sample preparation devices such as water purifiers and sample conditioners.
  • Sample preparation capabilities extend the range of the instrument into areas, such as on-line filtration, matrix elimination, neutralization, and ultratrace analysis.
  • Flexible flow rates support 2, 3, 4, and 5 mm column formats.
  • Column heater provides day-to-day consistency, ensuring reproducibility and stability. Preheating of the eluent prior to the column maintains the column temperature set by the user. A transparent cover allows viewing of the column without temperature disruption.

Achieve Results without the Problems and Cost of Manual Eluent Preparation and Now Automate Sample Preparation

Reagent-Free systems convert deionized water into high-purity eluents on-line, eliminating the labor of eluent preparation. In addition to being fully integrated, the ICS-2100 ships fully preconfigured, factory plumbed, and tested for immediate startup and performance. You begin to collect data within hours of installation. The ICS-2100 performs all types of IC separations using conductivity detection. With a space-conserving small-footprint design, the ICS-2100 occupies minimal bench space yet provides easy access to all vital system components. A new, integrated auxiliary valve available as an option enables a wide range of automated sample preparation techniques including on-line filtration, matrix elimination, and automatic reduced-volume reinjection of samples. Save time and money!


ICS-2100 Integrated Reagent-Free IC System Specifications

Analytical Pump and Fluidics
Type Serial dual-reciprocating pistons, microprocessor-controlled constant stroke, variable speed
Construction Chemically inert, metal-free PEEK pump heads and flow paths compatible with aqueous eluents of pH 0–14 and reversed-phase solvents
Pump Operating Pressure 0–35 MPa (0–5000 psi)
Flow Rate Range 0.00–5.00 mL/min without changing pump heads
Flow Precision <0.1%, typically
Flow Accuracy <0.1%, typically
Pressure Ripple <1% at 13.8 MPa (2000 psi) and 1.0 mL/min
Eluent On-Off Valve Standard
Piston Seal Wash Dual-pump head, wash can be continuous when connected to rinse solution supply
Pressure Alarm Limits Upper limit 0–35 MPa or 0–5000 psi in one unit (MPa or psi) increments; lower limit can be set up to one unit lower than upper limit
Vacuum Degas Yes, optional, automatic control
Eluent Bottles Polypropylene, up to 4 L volume
Eluent Bottle Pressure Not required
Injection Valve 6-port, 2-position Rheodyne valve, electrically activated
Columns Supported 2, 3, 4, and 5 mm i.d., maximum length 250 mm analytical column with 50 mm guard column
Column Heater Standard
Operating Temperature Range 30–60 °C (86–140 °F); minimum
5 °C above the ambient temperature. Settable range is equal to working range.
Temperature Accuracy ±0.5 °C at sensor; at 40 °C
Eluent Generation Standard
Eluent Types KOH, LiOH, NaOH
Gradient Profiles Option; Combination of unlimited number of linear, convex and concave positive and negative gradient profiles
Concentration Increments 0.01 mM
Concentration Range 0.1–100 mM (depending on eluent used)
Flow Rate 0.1–3.0 mL/min
Maximum Operating Pressure 21 MPa (3000 psi)
Maximum Solvent Concentration Anions: 25% methanol
Cations: no solvents
Auxiliary Power Supply Standard
Current Constant, 0–200 mA at up to 35 V
Alarms Overvoltage and overcurrent alarms; linked to pump flow to protect devices from power on at zero flow
Auxiliary Valve (Optional) One 6- or 10-port, 2 position high-pressure Rheodyne valve, fully inert PEEK construction, electrically activated. Field installable, integrated into instrument
Eluent Regeneration Support Yes, with optional RFIC-ER Startup kit
Eluents Carbonate and carbonate/bicarbonate combinations up to 20 mM; MSA up to 34 mM
Flow Rates 0.01–2.00 mL/min
Continuous Operation (4 L of eluent) Up to 28 days or 2000 samples, typically
Always On/Always Ready Capable Yes, standard feature
Remains Fully Calibrated for Extended Periods
(<28 days)
Yes, standard feature. Results are traceable to a single calibration
System Wellness Consumables usage monitoring for predictive maintenance
Maximum Operating Pressure 21 MPa (3000 psi)
Operating Temperature Range 4–40 °C
Suppressors and Control
Chemical Suppression 2 mm and 4 mm anion and cation, membrane suppression bed type
Displacement Chemical Regeneration 2 mm and 4 mm anion and cation, membrane suppression bed type
Electrolytic Suppression- Self Regenerating. 2 mm and 4 mm anion and cation. Both membrane and MonoDisk suppression bed types available
Electrolytic Suppression- Self Regenerating with External Water Mode 2 mm and 4 mm anion and cation. Both membrane and MonoDisk suppression bed types available
Current Control Range SRS®:
4 mm, 0–300 mA in 1 mA increments
2 mm, 0–100 mA in 1 mA increments
AES®: 0–150 mA in 1 mA increments
CMD: 0–500 mA in 1 mA increments
SRN: 0–500 mA in 1 mA increments
CMD: 0–500 mA in 1 mA increments
Salt Converter Available in 2 and 4 mm versions
AMMS-ICE Available in 2 and 4 mm versions
Carbonic Acid Removal for Anions Yes:
ASRS® 300 plus CRD 200 for hydroxide eluents
ASRS 300 with CRD 300 for carbonate eluents
Non-Suppressed Chromatography Yes, supported
Suppressor Wear Parts None; peristaltic pump and inline filters are not required
Suppression Capacity Anion SRS 300 (4 mm): 200 µeq/min
Cation SRS 300 (4 mm): 110 µeq/min
Anion SRS 300 (2 mm): 50 µeq/min
Cation SRS 300 (2 mm): 37.5 µeq/min
Anion MMS™ 300 (4 mm): 150 µeq/min
Cation MMS 300 (4 mm): 150 µeq/min
Anion MMS 300 (2 mm): 37.5 µeq/min
Cation MMS 300 (2 mm): 37.5 µeq/min
Anion AES: 25 µeq/min
Cation AES:25 µeq/min
Void Volumes SRS 300 (4 mm): <50 µL
SRS 300 (2 mm): <15 µL
MMS 300 (4 mm): <50 µL
MMS 300 (2 mm): <15 µL
AMMS-ICE 300 (4 mm): <50 µL
AMMS-ICE 300 (2 mm): <15 µL
AES (Anion or Cation): <35 µL
Conductivity Detector Electronics and Flow Cell
Type Microprocessor-controlled digital signal processor
Cell Drive 8 kHz square wave
Linearity 1% up to 1 mS/cm
Resolution 0.00238 nS/cm
Full-Scale Output Ranges Digital signal range 0–15,000 µS/cm
Analog signal range 0–15,000 µS/cm
Electronic Noise ±0.1 nS when background conductivity is 0–150 µS/cm
±2 nS when background conductivity is 151–3200 µS/cm
Filter Rise times from 0 to 10 s, user selectable
Temperature Compensation Fixed at 1.7%/ °C at cell temperature
Temperature Range Ambient +7 °C; 30–55 °C
Cell Electrodes Passivated 316 stainless steel. Compatible with MSA
Cell Body Chemically inert polymeric material
Cell Volume <1 µL
Heat Exchanger Inert, tortuous-path for low axial dispersion
Maximum Cell Operating Pressure 10 MPa (1500 psi)
Automation Using Autosampler Thermo Scientific Dionex AS-AP, AS-DV, AS-HV, or third-party Autosamplers
Sequential/Simultaneous Injection Yes, depending on autosampler capabilities
Automated Dilution Yes, available with AS-AP Autosampler
Dilution Factor, AS-AP Autosampler 1:1 to 1:1000
Dilution Time, AS-AP Autosampler 15 seconds with sample overlap
Inline Sample Degassing Yes, optional with CRD 200/300
Inline Filtration Yes, AS-DV Autosampler or inline filter
High Automation Flexibility Conditionals using Chromeleon® software and post run features
System Software and Control
Software Chromeleon Chromatography Data System software, supports Microsoft Windows® 7, XP, or Vista
Automated Procedure Wizards Yes, standard feature
Data Trending Plots Yes, numerical device parameters can be plotted
Virtual Column Simulator Yes; evaluation mode standard,
isocratic and gradient optional
Application Templates Yes, standard feature
Multivendor Automation Support of 3rd Party Instruments Yes, fully controls over 300 different instruments from more than 30 manufacturers, including GC, HPLC, and MS
3-D Software for PDA and MS Yes, optional
Customizable System Control Panels Yes, standard feature
System Status Virtual Channel Yes, standard feature
Power Failure Protection Yes, standard feature
Sequential Injection Yes, standard feature for independent dual system analysis
System Trigger Commands and Conditionals Yes, standard feature
Daily Audit Trail Yes, standard feature
Sample Audit Trail Yes, standard feature
Multiple Network Control and Network Failure Protection Yes, optional
System Calibration Storage Yes, factory, present and previous. Completely user selectable
Customized Reporting Yes, standard feature with unlimited report workbooks
Control Modes Full control through front panel and Chromeleon software; alternative control through TTL or relay closures; two relay outputs, two TTL outputs, four programmable inputs
Semi Automated System Qualification Yes, automated IQ/OQ/PQ procedures produce detailed, comprehensive qualification reports using minimal operator time
USB Communication Protocol One input; one built-in two-port USB hub
Physical Specifications
Dimensions (h × w × d) 56.1 cm × 22.4 cm × 53.3 cm
(22.1 in × 8.8 in × 21 in.)
Weight 24.5 kg (54 lb)
Power Requirements 100–240 V ac, 50–60 Hz, autoranging
Operating Temperature 4–40 °C (40–104 °F); cold-room-compatible (4 °C) as long as system power remains on
Operating Humidity Range 5–95% relative, non-condensing
Leak Detection Built-in, optical sensor


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